This feature enables you to assign the interrupts that support affinity settings to the specified CPUs. After that, the interrupt requests will be processed by the specified CPUs. As a best practice, do not assign the interrupts to isolated CPUs to make sure that the interrupts do not affect the tasks on the isolated CPUs.
On the top navigation bar, click Hosts. If the system has multiple clusters, select a cluster from the left navigation pane.
Select the target host, and then click the Advanced tab.
Click the Interrupt Affinity tab.
Set the state of interrupt affinity. If you enable interrupt affinity, click the Edit icon for a NUMA node, select the CPUs to bind, and then click OK.
Click Save.
Interrupt Affinity: Configure the interrupt affinity state of the host.